Bioassay of ICRF-159 for possible carcinogenicity.
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Bioassay of ICRF-159 for possible carcinogenicity.

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Published by Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Cancer Institute, Division of Cancer Cause and Prevention, Carcinogenesis Testing Program in Bethesda, Md .
Written in English


  • Carcinogens.,
  • Antineoplastic agents -- Toxicology.

Book details:

Edition Notes

SeriesDHEW publication -- no. (NIH) 78-1328, Carcinogenesis technical report series -- no. 78
The Physical Object
Pagination122 p. in various pagings :
Number of Pages122
ID Numbers
Open LibraryOL22412252M

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Bioassay of ICRF for possible carcinogenicity Published: () Bioassay of sulfisoxazole for possible carcinogenicity Published: () Bioassay of estradiol mustard for possible carcinogenicity Published: (). Conducted for the Carcinogenesis Testing Program, National Cancer Institute, by Southern Research Institute, by Southern Research Institute, Birmingham, Ala. NLM ID: [Book]. The NIH Library is a leading biomedical research library whose collection and services are developed to support the programs of the National Institutes of Health and selected U.S. Department of Health and Human Services (HHS) agencies. This digitized collection of NIH Annual Reports is provided as. National Cancer Institute (d) Bioassay of ICRF for possible carcinogenicity. CAS no – NCI carcinogenesis technical report series no 78, DHEW publication no (NIH) 78–, Washington, DC Google ScholarCited by: 8.

In book: Genotoxic Impurities, pp Regulatory agencies currently rely on rodent carcinogenicity bioassay data to predict whether or not a . The usefulness of mutagen-carcinogen correlations also depends on the quality of carcinogenicity data, and the statistical power to eliminate both false positives and false negatives. The quality of the Bioassay data was quite variable, often due to inconsistencies between experimental protocol and the established NCI by: 2. I i t Bioassay of agents in mice Bioassay of agents in rats (n=) (n=55) i r 0 t I (n) 44 TABLE 12 7 CHEMICALS WERE CLASSED AS NON-ALERTING IN STRUCTURE (SA-) BUT INDUCED TUMOURS IN 3 OR MORE TISSUES IN THE RAT (cf. TA THE SHADED % AND 25%) The Cited by: ORNL/EIS Contract No. Weng Information Division SCIENTIFIC RATIONALE FOR THE SELECTION OF TOXICITY TESTING METHODS: HUMAN HEALTH ASSESSMENT Robert H. Ross, John S. Drury, Michael G. Ryon, Mary L. Williams, John T. Ensminger, and M. Virginia Cone Health and Environmental Studies Program Information Center Complex Work .

In , Ames and Gold described a conundrum of “too many carcinogens” among chemicals tested in rodent bioassays. Their proposed nongenotoxic carcinogenic mechanism was amplification of the. draft survey and evaluation of in vitro toxicity test methods august prepared for office of toxic substances u.s. environmental protection agency washington, dc . This banner text can have markup.. web; books; video; audio; software; images; Toggle navigation. Why yet another volume in the series “Small Ring Compounds in Organic Synthesis” after five previous ones (Vol. , , , , )? Well, small ring chemistry is still flourishing, and probably even more than ever, at least as far as the applications of small rings in Organic Synthesis are concerned.